Plastic
surgeons countdown first full facial transplantation
First
studies reveal next steps in historic procedure
Even after news of the first partial facial transplantation performed
in France spread around the world, plastic surgeons have continued
to research how to make the first full facial transplantation
a reality. In the first peer-reviewed, scientific studies of their
kind, U.S. plastic surgeons demonstrated how to successfully complete
a full facial tissue transplantation from one human body to another,
reports the March issue of Plastic and Reconstructive Surgery®
(PRS), the official medical journal of the American Society of
Plastic Surgeons (ASPS).
"For the first time, we have scientific data that takes us
beyond traditional reconstructive techniques and partial facial
transplantation," said ASPS President Bruce Cunningham, MD.
"What we thought of as a possibility - reconstructing the
entire face of someone with a severe facial disfigurement, in
one surgery, from one complete facial skin flap taken from a donor
- is no longer just theory, but will become an actuality."
"Through these particular studies we have determined that
full facial tissue transplantation is a successful approach in
helping patients horribly disfigured by burns, accidents and other
trauma," said study lead author Maria Siemionow, MD, director
of plastic surgery research at the Cleveland Clinic. "The
transplantation of a facial tissue flap from one cadaver to another
has allowed us to do the following: estimate the time it takes
to perform this particular transplantation, perfect our technique
and visually confirm that a facial tissue flap is a match when
covering severe burns and other trauma."
Although traditional methods for facial reconstruction, which
include skin grafts and flaps, are reliable and effective techniques
for reconstructing the face, they may not be ideal, according
to the studies. It is nearly impossible to match the skin quality,
texture and color of the face with any other tissue available
on the body. In addition, it takes multiple grafts and surgeries
to successfully reconstruct the entire face. Many patients are
left with a patchy, unfavorable appearance, including large scars
and mismatched skin. The studies found the only way to surgically
match facial skin texture, pliability and color is through facial
transplantation.
"There is no doubt that facial transplantation can improve
the quality of life for patients, however, facial transplantation
will not replace traditional techniques," said Rod Rohrich,
MD, editor of PRS. "This is an exciting time in plastic surgery,
but it is important to remember that, at least in the near future,
facial transplantation will be a last resort procedure performed
on carefully selected patients on a case-by-case basis."
In the studies, doctors used cadavers to perform mock facial transplantations
in order to outline the necessary steps to transplant a human
face. Through these trials, they were able to visually show the
full extent of the procedure's outcome.
During the procedure it took surgeons approximately five hours
to perform the mock facial transplantation, this did not include
vessel and nerve repair. In living recipients, the authors estimate
the total length of surgery will be approximately 11-15 hours.
"Plastic surgeons have historically been at the forefront
of transplantation medicine," said Dr. Cunningham. "The
first successful hand transplantation was performed by a plastic
surgeon in 1998, as was the first kidney transplant in 1954. The
idea of tissue transplantation has opened a new era in this field
of medicine."
American Society of Plastic Surgeons